Rubella virus persists after vaccination in some patients with rare immune disorders

(Children's Hospital of Philadelphia) Some patients with rare primary immunodeficiency disorders may at risk for infection by rubella virus, and possibly serious skin inflammation, after receiving the rubella vaccine. Although the vaccine for rubella (German measles) has an established record of safety and effectiveness in the general population, patients with severe deficiencies in their immune defenses may be susceptible to side effects from the vaccine.